Centrifuge dryer competence Team

Solid-liquid separation, product washing, and subsequent drying are crucial processes in the API and pharmaceutical industries.

"Drying is the art of effective evaporation," as Serafima puts it. Mastering this involves ensuring the drying process is homogeneous, dust-free, reproducible in residual moisture, and as gentle as possible. Our TZT Centrifugal Dryer (FSD) employs fluidized bed drying with a revolutionary counter pulse sequence, offering superior performance compared to other technologies. Each crystal's surface is fully exposed during the hovering phase, ensuring excellent heat transfer and short drying times. The product is dried gently, without mechanical stress, achieving a consistent product temperature through continuous mixing. Serafima offers centrifugal dryers with batch capacities from 5 to 800 liters.

Typically, suspensions are dried in multiple steps, starting only when solid-liquid separation reaches its limits due to the higher energy requirements of thermal drying. Energy optimization is a key focus for manufacturers.

In process development, solid-liquid separation and drying are often treated separately. However, combining these processes yields the best results by minimizing project handling efforts and commissioning issues. Potent compounds play a crucial role in modern medications, necessitating stringent containment and Good Manufacturing Practices (GMPs) to prevent cross-contamination and protect workers.

Our unique TZT centrifugal dryer (FSD) addresses these challenges, offering sterility and containment in combined centrifugation and drying operations. Additional benefits include effective displacement washing, residue-free discharge, and fully automated C.I.P. and S.I.P.